Cis-Topo Study

The purpose of this study is to determine if two approved chemotherapy drugs (cisplatin and topotecan) can be used in tandem to shrink cancers of the cervix and/or vulva.

In the study, women with these types of cancer are given the medications over a 9-18 week period. Then, researchers monitor their progress to determine if their cancers shrink and become more treatable.

If the technique is successful it could limit – or eliminate - the need for radiation therapy (or combined chemoradiation), the current standard treatment for advanced cervical cancer. For patients with vulvar cancer, the treatment could also help them avoid surgery that involves more risk and greater tissue loss.

Last Updated on Thursday, 15 July 2010 21:27
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